Nguyen T and Song J. The Rsp CL bioconjugation system. Submitted & under review.

Ahn C*, Yang Y-A*, Neupane D, Nguyen T, Richards A, Sim JH, Mantis N, and Song J. Mechanisms of typhoid toxin neutralization by antibodies targeting receptor-binding and nuclease subunits. Submitted & under review (* co-first author). Available at SSRN: https://ssrn.com/abstract=3751789

Ahn C, Yang Y-A, and Song J. Early-life protection by maternal antibodies against Salmonella typhoid toxin. In revision.

Nguyen T*, Richards AF*, Neupane DP, Feathers JR, Yang Y-A, Sim JH, Byun H, Lee S, Ahn C, VanSlyke G, Fromme JC, Mantis NJ**, and Song J**. The structural basis of Salmonella A2B5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Submitted & under review. Available at SSRN: https://ssrn.com/abstract=3745287 or http://dx.doi.org/10.2139/ssrn.3745287

Lee S*, Yang Y-A*, Milano SK, Nguyen T, Ahn C, Sim JH, Thompson AJ, Hillpot EC, Yoo G, Paulson JC, and Song J. (2020). Salmonella typhoid toxin PltB subunit and its nontyphoidal Salmonella orthologue confer differential host adaptation and virulence. Cell Host & Microbe. 27: 1-13. (* co-first authors). DOI:10.1016/j.chom.2020.04.005

Highlighted in Previews (Cell Host & Microbe 2020, 27(6): 851-853).

Nguyen T*, Lee S*, Yang Y-A, Ahn C, Sim JH, Kei TG, Barnard KN, Yu H, Millano SK, Chen X, Parrish CR, and Song J. (2020). The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. (* co-first authors). PLOS Pathogens. 16(2): e1008336. DOI: 10.1371/journal.ppat.1008336

Yang Y, Higgins C, Rehman I, Galvao K, Brito I, Bicalho M, Song J, Wang H, and Bicalho R. (2019). The genomic diversity, virulence, and antimicrobial resistance of Klebsiella pneumoniae from cows and humans. Applied and Environmental Microbiology. 85 (6): e02654-18. DOI: 10.1128/AEM.02654-18

Yang Y-A, Chong A, and Song J. (2018). Why is Eradicating Typhoid Fever So Challenging: Implications for Vaccine and Therapeutic Design. Vaccines. 6 (3), 45. DOI: 10.3390/vaccines6030045

Yang Y-A, Lee S, Zhao J, Thompson AJ, McBride R, Tsogtbaatar B, Paulson JC, Nussinov R, Deng L, and Song J. (2018). In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennary glycan receptor. Nature Microbiology. 3 (2): 155-163. Epub Dec 4, 2017. DOI: 10.1038/s41564-017-0076-4

Highlighted in News and Views (Nature Microbiology 3 (2): 124-126.)

Liu Y, Qi L, Qi L, Ding T, Wang Z, Fu J, Hu M, Li M, Song J** (** co-senior author), and Liu X**. (2017). Temporal regulation of a Salmonella Typhimurium virulence factor by the transcriptional regulator YdcR. Molecular & Cellular Proteomics. 16 (9):1683-1693. DOI: 10.1074/mcp.M117.068296

Chong, A, Lee, S, Yang, Y-A, and Song J. (2017). The role of typhoid toxin in Salmonella Typhi virulence. Yale Journal of Biology & Medicine. 90 (2):283-290. PMCID: PMC5482304

Chang S-J, Song J, and Galán JE. (2016). Receptor-mediated sorting of typhoid toxin during its export from Salmonella Typhi-infected cells. Cell Host & Microbe. 20 (5):682-689. DOI: 10.1016/j.chom.2016.10.005

Song J*, Wilhelm CL*, Wangdi T, Maira-Litran T, Lee S-J, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Baumler AJ, Pier GB, Galán JE, and Yarovinsky F. (2016). Absence of TLR11 in mice does not confer susceptibility to Salmonella Typhi. Cell. 164 (5):827-8. (* co-first author). DOI: 10.1016/j.cell.2016.02.015

Deng L*, Song J* (* co-first author), Gao X*, Wang J, Yu H, Chen X, Varki N, Naito-Matsui Y, Galán JE, and Varki A. (2014). Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi. Cell. 159 (6):1290-9. DOI: 10.1016/j.cell.2014.10.057

Selected previous publications

Song J*, Gao X*, and Galán JE. (2013). Structure and function of the Salmonella Typhi chimaeric A₂B₅ typhoid toxin. Nature. 499(7458):350-354. (* co-first authors; Highlighted in News and Views, Highlighted in Faculty 1000). DOI: 10.1038/nature12377

Song J*, Willinger T*, Rongvaux A, Eynon EE, Stevens S, Manz MG, Flavell RA, and Galán JE. (2010). A mouse model for the human pathogen Salmonella Typhi. Cell Host & Microbe. 8(4):369-76. (* co-first authors). DOI: 10.1016/j.chom.2010.09.003

Song J*, Bishop BL*, Li G, Grady R, Stapleton A, and Abraham SN. (2009). TLR4-mediated expulsion of bacteria from infected bladder epithelial cells. Proc Natl Acad Sci USA. 106(35):14966-71. (* co-first authors). DOI: 10.1073/pnas.0900527106

Song J**, and Abraham SN. (2008). TLR-mediated immune responses in the urinary tract. Current Opinion in Microbiology. 11(1):66-73. (** corresponding author). DOI: 10.1016/j.mib.2007.12.001

Song J**, and Abraham SN. (2008). Innate and adaptive immune responses in the urinary tract. European Journal of Clinical Investigation. 2:21-8. (** corresponding author). DOI: 10.1111/j.1365-2362.2008.02005.x

Song J, Bishop BL, Li G, Duncan MJ, and Abraham SN. (2007). TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder. Cell Host & Microbe. 1(4):287-298. (Highlighted as a Featured article). DOI: 10.1016/j.chom.2007.05.007

Song J, Duncan MJ, Li G, Chan C, Grady R, Stapleton A, and Abraham SN. (2007). A novel TLR4 mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells. PLOS Pathogens. 3(4):e60. (Highlighted as Cover Story, Highlighted in Editor’s pick). DOI: 10.1371/journal.ppat.0030060

Bishop BL, Duncan MJ, Song J, Li G, Zaas D, and Abraham SN. (2007). Cyclic AMP-regulated exocytosis of E. coli from infected bladder epithelial cells. Nature Medicine. 13(5):625-630. (Highlighted in News and Views). DOI: 10.1038/nm1572