Yang Y-A*, Richards AF*, Nguyen T*, Sim JH, Feathers JR, Ahn C, Lee S, Byun HM, Slyke GV, Fromme JC, Mantis NJ**, and Song J**. (2020). Structure-function analysis of neutralizing antibodies that confer prophylactic and therapeutic protection against Salmonella typhoid toxin. (* co-first authors, ** co-senior authors). Cell. In revision.

Lee S*, Yang Y-A*, Milano SK, Nguyen T, Ahn C, Sim JH, Thompson AJ, Hillpot EC, Yoo G, Paulson JC, and Song J. (2020). Host adaptations of the Salmonella Typhi typhoid toxin and its orthologue from a nontyphoidal Salmonella. Cell Host & Microbe. Revision submitted.

Nguyen T*, Lee S*, Yang Y-A, Ahn C, Sim JH, Kei TG, Barnard KN, Yu H, Millano SK, Chen X, Parrish CR, and Song J. (2020). The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. (* co-first authors). PLoS Pathogens. In press. DOI: 10.1371/journal.ppat.1008336

Yang Y, Higgins C, Rehman I, Galvao K, Brito I, Bicalho M, Song J, Wang H, and Bicalho R. (2019). The genomic diversity, virulence, and antimicrobial resistance of Klebsiella pneumoniae from cows and humans. Applied and Environmental Microbiology. 85 (6): e02654-18. DOI: 10.1128/AEM.02654-18

Yang Y-A, Chong A, and Song J. (2018). Why is Eradicating Typhoid Fever So Challenging: Implications for Vaccine and Therapeutic Design. Vaccines. 6 (3), 45. DOI: 10.3390/vaccines6030045

Yang Y-A, Lee S, Zhao J, Thompson AJ, McBride R, Tsogtbaatar B, Paulson JC, Nussinov R, Deng L, and Song J. (2018). In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennary glycan receptor. Nature Microbiology. 3 (2): 155-163. Epub Dec 4, 2017. DOI: 10.1038/s41564-017-0076-4

Highlighted in News and Views (Nature Microbiology 3 (2): 124-126.)

Liu Y, Qi L, Qi L, Ding T, Wang Z, Fu J, Hu M, Li M, Song J**, and Liu X**. (2017). Temporal regulation of a Salmonella Typhimurium virulence factor by the transcriptional regulator YdcR. Molecular & Cellular Proteomics. 16 (9):1683-1693. (** co-senior authors). DOI: 10.1074/mcp.M117.068296

Chong, A, Lee, S, Yang, Y-A, and Song J. (2017). The role of typhoid toxin in Salmonella Typhi virulence. Yale Journal of Biology & Medicine. 90 (2):283-290. PMCID: PMC5482304

Chang S-J, Song J, and Galán JE. (2016). Receptor-mediated sorting of typhoid toxin during its export from Salmonella Typhi-infected cells. Cell Host & Microbe. 20 (5):682-689. DOI: 10.1016/j.chom.2016.10.005

Song J*, Wilhelm CL*, Wangdi T, Maira-Litran T, Lee S-J, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Baumler AJ, Pier GB, Galán JE, and Yarovinsky F. (2016). Absence of TLR11 in mice does not confer susceptibility to Salmonella Typhi. Cell. 164 (5):827-8. (* co-first authors). DOI: 10.1016/j.cell.2016.02.015

Deng L*, Song J*, Gao X*, Wang J, Yu H, Chen X, Varki N, Naito-Matsui Y, Galán JE, and Varki A. (2014). Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi. Cell. 159 (6):1290-9. (* co-first authors). DOI: 10.1016/j.cell.2014.10.057

Selected previous publications

Song J*, Gao X*, and Galán JE. (2013). Structure and function of the Salmonella Typhi chimaeric A₂B₅ typhoid toxin. Nature. 499(7458):350-354. (* co-first authors; Highlighted in News and Views, Highlighted in Faculty 1000). DOI: 10.1038/nature12377

Song J*, Willinger T*, Rongvaux A, Eynon EE, Stevens S, Manz MG, Flavell RA, and Galán JE. (2010). A mouse model for the human pathogen Salmonella Typhi. Cell Host & Microbe. 8(4):369-76. (* co-first authors). DOI: 10.1016/j.chom.2010.09.003

Song J*, Bishop BL*, Li G, Grady R, Stapleton A, and Abraham SN. (2009). TLR4-mediated expulsion of bacteria from infected bladder epithelial cells. Proc Natl Acad Sci USA. 106(35):14966-71. (* co-first authors). DOI: 10.1073/pnas.0900527106

Song J**, and Abraham SN. (2008). TLR-mediated immune responses in the urinary tract. Current Opinion in Microbiology. 11(1):66-73. (** corresponding author). DOI: 10.1016/j.mib.2007.12.001

Song J**, and Abraham SN. (2008). Innate and adaptive immune responses in the urinary tract. European Journal of Clinical Investigation. 2:21-8. (** corresponding author). DOI: 10.1111/j.1365-2362.2008.02005.x

Song J, Bishop BL, Li G, Duncan MJ, and Abraham SN. (2007). TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder. Cell Host & Microbe. 1(4):287-298. (Highlighted as a Featured article). DOI: 10.1016/j.chom.2007.05.007

Song J, Duncan MJ, Li G, Chan C, Grady R, Stapleton A, and Abraham SN. (2007). A novel TLR4 mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells. PLOS Pathogens. 3(4):e60. (Highlighted as Cover Story, Highlighted in Editor’s pick). DOI: 10.1371/journal.ppat.0030060

Bishop BL, Duncan MJ, Song J, Li G, Zaas D, and Abraham SN. (2007). Cyclic AMP-regulated exocytosis of E. coli from infected bladder epithelial cells. Nature Medicine. 13(5):625-630. (Highlighted in News and Views). DOI: 10.1038/nm1572